Gingko Biloba Liquid Extract (Eco Certified & Paraben Free)

Description

Gingko Biloba tree is a long living tree. The plant grow slowly each year. The extract is extracted from the leaves of the tree. It is native to Asia, Korea and Japan.

There are two compounds that contributes to the therapeutic actions which is the flavonoids and terpenes. These compounds are the basis for its therapeutic actions.

Anti-oxidant
Ginkgo extract acts as an antioxidant by scavenging free radicals and inhibiting the generation of reactive oxygen species. The antioxidant compounds identified in ginkgo are mainly flavonoids (Tiedtke J., et al., 2006).
In vitro studies have shown that standardized solutions of Ginkgo biloba (EGb761) inhibit the formation of hydroxyl radical by 65% and adriamycin radical by 50%, thus reducing lipid peroxidation. Additionally, antioxidant activity against superoxide anion, nitric oxide and diphenyl-picrylhydrazyl has also been observed. Studies carried out with healthy volunteers showed that ginkgo extracts were more effective than β-carotene and vitamin E to reduce UV-induced oxidative stress in epidermal cells. The action mechanism seems to involve the group of flavonoids (Alonso, J, 2004).
Thus, ginkgo extract is recommendable to formulate cosmetic products for the protection of skin and hair integrity against oxidative agents.

Anti-inflammatory activity
This activity is due to flavonoids and terpenes in ginkgo leaves.
Kwak W-J et al. (2002) studied the anti-inflammatory actions of ginkgetin, a biflavone from Ginkgo biloba leaves. Previous research had revealed that ginkgetin was a phospholipase A2 inhibitor with potent anti-arthritic activity in rats and analgesic activity. The authors investigated possible effects of ginkgetin on the cyclooxygenases COX-1 and COX-2 including its possible in vivo effects. The results suggested that ginkgetin from G. biloba leaves had anti-inflammatory activity based on its capacity to down-regulate COX-2 induction.
Cheon B.S. et al. (2000) studied the inhibitory activity of bilobetin and ginkgetin on nitric oxide (NO) production in lipopolysaccharide-induced macrophage cell lines (RAW 264.7). Nitric oxide (NO) produced by inducible NO synthase (iNOS) is known to play an important role in inflammatory disorders. The results showed that bilobetin and ginkgetin inhibited NO production from lipopolysaccharide-induced RAW 264.7 cells at concentrations higher than 10 μM. Such inhibition was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activi

Lipolysis stimulating activity- Several studies suggest that a dimeric flavonoid-rich fraction of Ginkgo biloba has anti-inflammatory and vasokinetic properties. It promotes blood micro-circulation and lipolysis in the adipose tissue.

Appearance: Light yellow liquid

Recommended dosage: 0.5-5%

Solubility: Soluble in aqueous solution

Product Origin: Spain